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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 1
1976 2
1977 2
1978 5
1979 1
1980 2
1981 2
1982 1
1983 2
1984 1
1985 3
1986 1
1987 2
1988 1
1989 1
1990 3
1991 2
1992 2
1993 2
1994 2
1996 2
1997 3
1998 3
1999 3
2000 3
2001 6
2002 2
2003 5
2004 6
2005 4
2006 7
2007 5
2008 13
2009 5
2010 6
2011 8
2012 3
2013 4
2014 4
2015 6
2016 5
2017 7
2018 6
2019 11
2020 7
2021 4
2022 1
2023 5
2024 1

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172 results

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Page 1
The effects of hypoalbuminaemia on optimizing antibacterial dosing in critically ill patients.
Ulldemolins M, Roberts JA, Rello J, Paterson DL, Lipman J. Ulldemolins M, et al. Clin Pharmacokinet. 2011 Feb;50(2):99-110. doi: 10.2165/11539220-000000000-00000. Clin Pharmacokinet. 2011. PMID: 21142293 Review.
All relevant articles that described the pharmacokinetics and/or pharmacodynamics of highly protein-bound antibacterials in critically ill patients with hypoalbuminaemia and conserved renal function were reviewed. ...In conclusion, altered antibacterial-albumin bind …
All relevant articles that described the pharmacokinetics and/or pharmacodynamics of highly protein-bound antibacterials in criticall …
The structure and existence of solutions of the problem of consumption with satiation in continuous time.
Smoczynski P, Miles S. Smoczynski P, et al. PLoS One. 2019 May 9;14(5):e0216383. doi: 10.1371/journal.pone.0216383. eCollection 2019. PLoS One. 2019. PMID: 31071121 Free PMC article.
We show that the differential equations have no solutions in the C1 class but that solutions exist in a wider space of functions, namely, the space of functions of bounded variation with non-negative Borel measures as controls. ...We prove the conjectu …
We show that the differential equations have no solutions in the C1 class but that solutions exist in a wider space of functions, nam …
Cooperativity of α-Synuclein Binding to Lipid Membranes.
Makasewicz K, Wennmalm S, Stenqvist B, Fornasier M, Andersson A, Jönsson P, Linse S, Sparr E. Makasewicz K, et al. ACS Chem Neurosci. 2021 Jun 16;12(12):2099-2109. doi: 10.1021/acschemneuro.1c00006. Epub 2021 Jun 2. ACS Chem Neurosci. 2021. PMID: 34076426 Free PMC article.
Cooperative binding is a key feature of metabolic pathways, signaling, and transport processes. It provides tight regulation over a narrow concentration interval of a ligand, thus enabling switching to be triggered by small concentration variations. ...Positive coop …
Cooperative binding is a key feature of metabolic pathways, signaling, and transport processes. It provides tight regulation over a narrow c …
Thyroid function tests: Thyroid disease: assessment and management: Evidence review C.
National Guideline Centre (UK). National Guideline Centre (UK). London: National Institute for Health and Care Excellence (NICE); 2019 Nov. London: National Institute for Health and Care Excellence (NICE); 2019 Nov. PMID: 35129920 Free Books & Documents. Review.
This avoids situations where variation in thyroid hormone binding proteins rather than thyroid function per se is responsible for abnormal test results. ...Other indications for FT3 include exclusion of T3 toxicosis (when TSH is suppressed but FT4 is within the refe …
This avoids situations where variation in thyroid hormone binding proteins rather than thyroid function per se is responsible …
Uncertainty Propagation for the Structures with Fuzzy Variables and Uncertain-but-Bounded Variables.
Xia Y, Ding L, Liu P, Tang Z. Xia Y, et al. Materials (Basel). 2023 Apr 25;16(9):3367. doi: 10.3390/ma16093367. Materials (Basel). 2023. PMID: 37176247 Free PMC article.
Random variables are usually employed to define uncertain factors with sufficient samples to accurately estimate probability density functions (PDFs). Uncertain-but-bounded variables are usually employed to define uncertain factors with limited samples that cannot a …
Random variables are usually employed to define uncertain factors with sufficient samples to accurately estimate probability density func …
Clinical pharmacokinetics and pharmacological effects of carbamazepine and carbamazepine-10,11-epoxide. An update.
Bertilsson L, Tomson T. Bertilsson L, et al. Clin Pharmacokinet. 1986 May-Jun;11(3):177-98. doi: 10.2165/00003088-198611030-00001. Clin Pharmacokinet. 1986. PMID: 3524954 Review.
Most oral formulations of carbamazepine are well absorbed with high bioavailability. The drug is 75% bound to plasma proteins. The degree of protein binding shows little variation between different subjects, and there is no need to monitor free rather than total pla …
Most oral formulations of carbamazepine are well absorbed with high bioavailability. The drug is 75% bound to plasma proteins. The de …
Use of ANOVA to estimate inter- and intra-reader variability for a group of readers in thorough QT/QTc studies.
Natekar M, Mahajan V, Satra A, O'Kelly M, Karnad DR. Natekar M, et al. Clin Pharmacol Ther. 2008 Mar;83(3):489-91. doi: 10.1038/sj.clpt.6100481. Epub 2008 Jan 9. Clin Pharmacol Ther. 2008. PMID: 18183035 Review.
Since the measurement of the QT interval is a relatively subjective assessment, the ECGs must be analyzed in a central ECG laboratory by "a few skilled readers." ...First, as a measure of the assay sensitivity, the study must include an active control known to prolong the …
Since the measurement of the QT interval is a relatively subjective assessment, the ECGs must be analyzed in a central ECG laboratory …
The genetic architecture of quantitative traits.
Mackay TF. Mackay TF. Annu Rev Genet. 2001;35:303-39. doi: 10.1146/annurev.genet.35.102401.090633. Annu Rev Genet. 2001. PMID: 11700286 Review.
Phenotypic variation for quantitative traits results from the segregation of alleles at multiple quantitative trait loci (QTL) with effects that are sensitive to the genetic, sexual, and external environments. ...The ease with which QTL can be mapped to genomic interval …
Phenotypic variation for quantitative traits results from the segregation of alleles at multiple quantitative trait loci (QTL) with e …
Quantification of lymphatic function for investigation of lymphedema: depot clearance and rate of appearance of soluble macromolecules in blood.
Pain SJ, Nicholas RS, Barber RW, Ballinger JR, Purushotham AD, Mortimer PS, Peters AM. Pain SJ, et al. J Nucl Med. 2002 Mar;43(3):318-24. J Nucl Med. 2002. PMID: 11884490 Free article.
RESULTS: (99m)Tc-HSA cleared from the depot consistently faster than (111)In-HSA (P = 0.001). The proportions of radionuclide remaining bound to protein in venous blood were higher for (99m)Tc than for (111)In. ...We conclude that (111)In dissociates from HSA in the depot …
RESULTS: (99m)Tc-HSA cleared from the depot consistently faster than (111)In-HSA (P = 0.001). The proportions of radionuclide remaining b …
Pharmacokinetics of nonsteroidal anti-inflammatory drugs in synovial fluid.
Day RO, McLachlan AJ, Graham GG, Williams KM. Day RO, et al. Clin Pharmacokinet. 1999 Mar;36(3):191-210. doi: 10.2165/00003088-199936030-00002. Clin Pharmacokinet. 1999. PMID: 10223168 Review.
The mean partition coefficient of most NSAIDs between synovial fluid and plasma is approximately 0.6. The NSAIDs are highly protein-bound, and the lower mean concentrations in synovial fluid are largely because of the lower concentrations of the binding protein, albumin. T …
The mean partition coefficient of most NSAIDs between synovial fluid and plasma is approximately 0.6. The NSAIDs are highly protein-bound …
172 results